Autologous stem cell transplantation leads to a change in proinflammatory plasma cytokine profile of patients with juvenile dermatomyositis correlating with disease activity.

نویسندگان

  • F Bellutti Enders
  • E M Delemarre
  • J Kuemmerle-Deschner
  • P van der Torre
  • N M Wulffraat
  • B P Prakken
  • A van Royen-Kerkhof
  • F van Wijk
چکیده

a change in proinflammatory plasma cytokine profile of patients with juvenile dermatomyositis correlating with disease activity Juvenile dermatomyositis ( JDM) is a rare autoimmune disorder, affecting mainly muscles and skin. The mainstay of treatment is high dose corticosteroids, combined with other immunosuppressive drugs. In about 30% of patients, the disease cannot be controlled despite multiple treatment interventions. Autologous stem cell transplantation (aSCT) has been reported as a last resort treatment in refractory patients with autoimmune

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عنوان ژورنال:
  • Annals of the rheumatic diseases

دوره 74 1  شماره 

صفحات  -

تاریخ انتشار 2015